Revlimid
lenalidomide
lenalidomide
This medicine is subject to additional monitoring. This will allow quick identification of new safety information. You can help by reporting any side effects you may get. See the end of section 4 for how to report side effects.
Keep this leaflet. You may need to read it again.
If you have any further questions, ask your doctor or pharmacist.
This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
If you get any side effects talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
What Revlimid is and what it is used for
What you need to know before you take Revlimid
How to take Revlimid
Possible side effects
How to store Revlimid
Contents of the pack and other information
Revlimid contains the active substance ‘lenalidomide’. This medicine belongs to a group of medicines which affect how your immune system works.
Revlimid is used in adults for:
Multiple myeloma
Myelodysplastic syndromes
Mantle cell lymphoma
Follicular lymphoma
Multiple myeloma is a type of cancer which affects a certain kind of white blood cell, called the plasma cell. These cells collect in the bone marrow and divide, becoming out of control. This can damage the bones and kidneys.
Multiple myeloma generally cannot be cured. However, the signs and symptoms can be greatly reduced or disappear for a period of time. This is called a ‘response’.
Newly diagnosed multiple myeloma – in patients who have had a bone marrow transplant
Revlimid is used on its own as a maintenance therapy after patients have recovered enough following a bone marrow transplant.
Newly diagnosed multiple myeloma – in patients who cannot have a bone marrow transplant Revlimid is taken with other medicines. These may include:
a chemotherapy medicine called ‘bortezomib’
an anti-inflammatory medicine called ‘dexamethasone’
a chemotherapy medicine called ‘melphalan’ and
an immunosuppressant medicine called ‘prednisone’.
You will take these other medicines at the start of treatment and then continue to take Revlimid on its own.
If you are aged 75 years or older or have moderate to severe kidney problems - your doctor will check you carefully before starting treatment.
Multiple myeloma – in patients who have had treatment before
Revlimid is taken together with an anti-inflammatory medicine called ‘dexamethasone’.
Revlimid can stop the signs and symptoms of multiple myeloma getting worse. It has also been shown to delay multiple myeloma from coming back following treatment.
MDS are a collection of many different blood and bone marrow diseases. The blood cells become abnormal and do not function properly. Patients can experience a variety of signs and symptoms including a low red blood cell count (anaemia), the need for a blood transfusion, and be at risk of infection.
Revlimid is used alone to treat adult patients who have been diagnosed with MDS, when all of the following apply:
you need regular blood transfusions to treat low levels of red blood cells (‘transfusion-dependent anaemia’)
you have an abnormality of cells in the bone marrow called an ‘isolated deletion 5q cytogenetic abnormality’. This means your body does not make enough healthy blood cells
other treatments have been used before, are not suitable or do not work well enough.
Revlimid can increase the number of healthy red blood cells that the body produces by reducing the number of abnormal cells:
this can reduce the number of blood transfusions needed. It is possible that no transfusions will be needed.
MCL is a cancer of part of the immune system (the lymph tissue). It affects a type of white blood cell called ‘B-lymphocytes’ or B-cells. MCL is a disease where B-cells grow in an uncontrolled way and build up in the lymph tissue, bone marrow or blood.
Revlimid is used alone to treat adult patients who have previously been treated with other medicines.
FL is a slow growing cancer that affects the B-lymphocytes. These are a type of white blood cells that help your body fight infection. When you have FL, too many of these B-lymphocytes may collect in your blood, bone marrow, lymph nodes and spleen.
Revlimid is taken together with another medicine called ‘rituximab’ for the treatment of adult patients with previously treated follicular lymphoma.
Revlimid works by affecting the body’s immune system and directly attacking the cancer. It works in a number of different ways:
by stopping the cancer cells developing
by stopping blood vessels growing in the cancer
by stimulating part of the immune system to attack the cancer cells.
if you are pregnant, think you may be pregnant or are planning to become pregnant, as Revlimid is expected to be harmful to an unborn child (see section 2, ‘Pregnancy, breast-feeding and contraception – information for women and men’).
if you are able to become pregnant, unless you follow all the necessary measures to prevent you from becoming pregnant (see section 2, ‘Pregnancy, breast-feeding and contraception – information for women and men’). If you are able to become pregnant, your doctor will record with each prescription that the necessary measures have been taken and provide you with this confirmation.
if you are allergic to lenalidomide or any of the other ingredients of this medicine listed in section 6. If you think you may be allergic, ask your doctor for advice.
If any of these apply to you, do not take Revlimid. Talk to your doctor if you are not sure.
you have had blood clots in the past - you have an increased risk of developing blood clots in the veins and arteries during treatment
you have any signs of an infection, such as a cough or fever
you have or have ever had previous viral infection, particularly: hepatitis B infection, varicella zoster, HIV. If you are in doubt, talk to your doctor. Treatment with Revlimid may cause the virus to become active again, in patients who carry the virus. This results in a recurrence of the infection. Your doctor should check whether you have ever had hepatitis B infection
you have kidney problems - your doctor may adjust your dose of Revlimid
you have had a heart attack, have ever had a blood clot, or if you smoke, have high blood pressure or high cholesterol levels
you have had an allergic reaction whilst taking thalidomide (another medicine used to treat multiple myeloma) such as rash, itching, swelling, dizziness or trouble breathing
you have experienced in the past a combination of any of the following symptoms: widespread rash, red skin, high body temperature, flu-like symptoms, liver enzyme elevations, blood abnormalities (eosinophilia), enlarged lymph nodes – these are signs of a severe skin reaction called Drug Reaction with Eosinophilia and Systemic Symptoms which is also known as DRESS or drug hypersensitivity syndrome. (see also section 4 “Possible side effects”).
If any of the above apply to you, tell your doctor, pharmacist or nurse before starting treatment. At any time during or after your treatment, tell your doctor or nurse immediately if you:
experience blurred, loss of or double vision, difficulty speaking, weakness in an arm or a leg, a change in
the way you walk or problems with your balance, persistent numbness, decreased sensation or loss of sensation, memory loss or confusion. These may all be symptoms of a serious and potentially fatal brain condition known as progressive multifocal leukoencephalopathy (PML). If you had these symptoms prior to treatment with Revlimid, tell your doctor about any change in these symptoms.
experience shortness of breath, tiredness, dizziness, pain in the chest, a faster heartbeat, or swelling in the legs or ankles. These may be symptoms of a serious condition known as pulmonary hypertension (see section 4).
Before and during the treatment with Revlimid you will have regular blood tests. This is because Revlimid may cause a fall in the blood cells that help fight infection (white blood cells) and help the blood to clot (platelets).
Your doctor will ask you to have a blood test:
before treatment
every week for the first 8 weeks of treatment
then at least every month after that.
You may be evaluated for signs of cardiopulmonary problems before and during the treatment with lenalidomide.
For patients with MDS taking Revlimid
If you have MDS, you may be more likely to get a more advanced condition called acute myeloid leukaemia (AML). In addition, it is not known how Revlimid affects the chances of you getting AML. Your doctor may therefore do tests to check for signs which may better predict the likelihood of you getting AML during your treatment with Revlimid.
For patients with MCL taking Revlimid
Your doctor will ask you to have a blood test:
before treatment
every week for the first 8 weeks (2 cycles) of treatment
then every 2 weeks in cycles 3 and 4 (see section 3 ‘Treatment cycle’ for more information)
after this it will happen at the start of each cycle and
at least every month.
For patients with FL taking Revlimid
Your doctor will ask you to have a blood test:
before treatment
every week for the first 3 weeks (1 cycle) of treatment
then every 2 weeks in cycles 2 to 4 (see Section 3 ‘Treatment cycle’ for more information)
After this it will happen at the start of each cycle and
at least every month.
Your doctor may check if you have a high total amount of tumour throughout the body, including your bone marrow. This could lead to a condition where the tumours break down and cause unusual levels of chemicals in the blood which can lead to kidney failure (this condition is called ‘Tumour Lysis Syndrome’).
Your doctor may check you for changes to your skin such as red spots or rashes.
Your doctor may adjust your dose of Revlimid or stop your treatment based on the results of your blood tests and on your general condition. If you are newly diagnosed, your doctor may also assess your treatment based on your age and other conditions you already have.
You should not donate blood during treatment and for at least 7 days after the end of treatment.
Revlimid is not recommended for use in children and adolescents under 18 years.
If you are aged 75 years or older or have moderate to severe kidney problems - your doctor will check you carefully before starting treatment.
Tell your doctor or nurse if you are taking or have recently taken any other medicines. This is because Revlimid can affect the way some other medicines work. Also, some other medicines can affect the way Revlimid works.
In particular, tell your doctor or nurse if you are taking any of the following medicines:
some medicines used to prevent pregnancy such as oral contraceptives, as they may stop working
some medicines used for heart problems – such as digoxin
some medicines used to thin the blood – such as warfarin.
For women taking Revlimid
You must not take Revlimid if you are pregnant, as it is expected to be harmful to an unborn baby.
You must not become pregnant while taking Revlimid. Therefore you must use effective methods of contraception if you are a woman of childbearing potential (see ‘Contraception’).
If you do become pregnant during your treatment with Revlimid, you must stop the treatment and inform your doctor immediately.
For men taking Revlimid
If your partner becomes pregnant whilst you are taking Revlimid, you should inform your doctor immediately. It is recommended that your partner seeks medical advice.
You must also use effective methods of contraception (see ‘Contraception’).
You must not breast-feed when taking Revlimid, as it is not known if Revlimid passes into breast milk.
For women taking Revlimid
Before starting the treatment, ask your doctor if you are able to become pregnant, even if you think this is unlikely.
If you are able to become pregnant
you will have pregnancy tests under the supervision of your doctor (before every treatment, at least every 4 weeks during treatment, and at least 4 weeks after the treatment has finished) except where it has been confirmed that the fallopian tubes have been severed and sealed, to stop eggs from reaching the uterus (tubal sterilisation)
AND
you must use effective methods of contraception for at least 4 weeks before starting treatment, during treatment, and until at least 4 weeks after stopping treatment. Your doctor will advise you on appropriate methods of contraception.
For men taking Revlimid
Revlimid passes into human semen. If your female partner is pregnant or able to become pregnant, and she does not use effective methods of contraception, you must use condoms during treatment and for at least 7 days after the end of treatment, even if you have had a vasectomy.
Do not drive or operate machines if you feel dizzy, tired, sleepy, have vertigo or blurred vision after taking Revlimid.
Revlimid contains lactose. If you have been told by your doctor that you have intolerance to some sugars, contact your doctor before taking this medicine.
Revlimid must be given to you by healthcare professionals with experience in treating multiple myeloma, MDS, MCL or FL.
When Revlimid is used to treat multiple myeloma in patients who cannot have a bone marrow transplant or have had other treatments before, it is taken with other medicines (see section 1 ‘What Revlimid is used for’).
When Revlimid is used to treat multiple myeloma in patients who have had a bone marrow transplant or to treat patients with MDS or MCL, it is taken alone.
When Revlimid is used to treat follicular lymphoma, it is taken with another medicine called ‘rituximab’.
Always take Revlimid exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
If you are taking Revlimid in combination with other medicines, you should refer to the package leaflets for these medicines for further information on their use and effects.
Revlimid is taken on certain days over 3 weeks (21 days).
Every 21 days is called a ‘treatment cycle’.
Depending on the day of the cycle, you will take one or more of the medicines. However, on some days you do not take any of the medicines.
After completing every 21-day cycle, you should start a new ‘cycle’ over the next 21 days. OR
Revlimid is taken on certain days over 4 weeks (28 days).
Every 28 days is called a ‘treatment cycle’.
Depending on the day of the cycle, you will take one or more of the medicines. However, on some days you do not take any of the medicines.
After completing every 28-day cycle, you should start a new ‘cycle’ over the next 28 days.
Before you start treatment, your doctor will tell you:
how much Revlimid you should take
how much of the other medicines you should take in combination with Revlimid, if any
on what days of your treatment cycle to take each medicine.
swallow the capsules whole, preferably with water.
do not break, open or chew the capsules. If powder from a broken Revlimid capsule makes contact with the skin, wash the skin immediately and thoroughly with soap and water.
healthcare professionals, caregivers and family members should wear disposable gloves when handling the blister or capsule. Gloves should then be removed carefully to prevent skin exposure, placed in a sealable plastic polyethylene bag and disposed of in accordance with local requirements. Hands should then be washed thoroughly with soap and water. Women who are pregnant or suspect they may be pregnant should not handle the blister or capsule.
the capsules can be taken either with or without food.
you should take Revlimid at about the same time on the scheduled days.
To remove the capsule from the blister:
press only one end of the capsule out to push it through the foil
do not put pressure on the centre of the capsule, as this can cause it to break.
Revlimid is taken in treatment cycles, each cycle lasting 21 or 28 days (see above ‘Treatment cycle’). You should continue the cycles of treatment until your doctor tells you to stop.
If you take more Revlimid than was prescribed, tell your doctor immediately.
If you forget to take Revlimid at your regular time and:
less than 12 hours have passed - take your capsule immediately.
more than 12 hours have passed - do not take your capsule. Take your next capsule at the usual time the next day.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Like all medicines, Revlimid can cause side effects, although not everybody gets them.
Hives, rashes, swelling of eyes, mouth or face, difficulty breathing, or itching, which may be symptoms of serious types of allergic reactions called angioedema and anaphylactic reaction.
A serious allergic reaction that may begin as a rash in one area but spread with extensive loss of skin over the whole body (Stevens-Johnson syndrome and/or toxic epidermal necrolysis).
Widespread rash, high body temperature, liver enzyme elevations, blood abnormalities (eosinophilia), enlarged lymph nodes and other body organs involvement (Drug Reaction with Eosinophilia and Systemic Symptoms which is also known as DRESS or drug hypersensitivity syndrome). See also section 2.
Fever, chills, sore throat, cough, mouth ulcers or any other symptoms of infection including within the bloodstream (sepsis)
Bleeding or bruising in the absence of injury
Chest pain or leg pain
Shortness of breath
Bone pain, muscle weakness, confusion or tiredness that might be due to high level of calcium in the blood.
Revlimid may reduce the number of white blood cells that fight infection and also the blood cells which help the blood to clot (platelets) which may lead to bleeding disorders such as nosebleeds and bruising.
Revlimid may also cause blood clots in the veins (thrombosis).
It is important to note that a small number of patients may develop additional types of cancer, and it is possible that this risk may be increased with Revlimid treatment. Therefore your doctor should carefully evaluate the benefit and risk when you are prescribed Revlimid.
A fall in the number of red blood cells which may cause anaemia leading to tiredness and weakness
Rashes, itching
Muscle cramps, muscle weakness, muscle pain, muscle aches, bone pain, joint pain, back pain, pain in the extremities
Generalised swelling including swelling of your arms and legs
Weakness, tiredness
Fever and flu like symptoms including fever, muscle ache, headache, earache, cough and chills
Numbness, tingling or burning sensation to the skin, pains in hands or feet, dizziness, tremor
Decreased appetite, change in the way things taste
Increase in pain, tumour size or redness around the tumour
Weight loss
Constipation, diarrhoea, nausea, vomiting, stomach pain, heartburn
Low levels of potassium or calcium and/or sodium in the blood
Thyroid functioning less than it should be
Leg pain (which could be a symptom of thrombosis), chest pain or shortness of breath (which may be a symptom of blood clots in the lungs, called pulmonary embolism)
Infections of all types, including infection of the sinuses that surround the nose, infection of the lung and the upper respiratory tract
Shortness of breath
Blurred vision
Clouding of your eye (cataract)
Kidney problems which include kidneys not working properly or not being able to maintain normal function
Abnormal liver test results
Increase in liver test results
Changes to a protein in the blood that can cause swelling of the arteries (vasculitis)
Increases in your blood sugar levels (diabetes)
Decreases in your blood sugar levels
Headache
Nosebleed
Dry skin
Depression, mood change, difficulty sleeping
Cough
A fall in blood pressure
A vague feeling of bodily discomfort, feeling bad
Sore inflamed mouth, dry mouth
Dehydration
Destruction of red blood cells (haemolytic anaemia)
Certain types of skin tumour
Bleeding of the gums, stomach, or bowels
Increased blood pressure, slow, fast or irregular heart beat
Increase in the amount of a substance which results from normal and abnormal breakdown of red blood cells
Increase in a type of protein that indicates inflammation in body
Darkening of your skin, discoloration of your skin resulting from bleeding underneath, typically caused by bruising, swelling of skin filled with blood, bruise
Increase in uric acid in the blood
Skin eruptions, redness of skin, cracking, flaking or peeling skin, hives
Increased sweating, night sweats
Difficulty swallowing, sore throat, difficulty with voice quality or voice changes
Runny nose
Production of much more or much less urine than usual or the inability to control when to urinate
Passing blood in the urine
Shortness of breath especially when lying down (which may be a symptom of heart failure)
Difficulty getting an erection
Stroke, fainting, vertigo (problem with inner ear which leads to feeling that everything is spinning), temporary loss of consciousness
Chest pain spreading to the arms, neck, jaw, back or stomach, feeling sweaty and breathless, feeling sick or vomiting, which may be symptoms of a heart attack (myocardial infarction)
Muscle weakness, lack of energy
Neck pain, chest pain
Chills
Joint swelling
Bile flow from liver slowed or blocked
Low levels of phosphate or magnesium in the blood
Difficulty speaking
Liver injury
Impaired balance, difficulty moving
Deafness, ringing in the ears (tinnitus)
Nerve pain, unpleasant abnormal sensation especially to touch
An excess of iron in the body
Thirst
Confusion
Toothache
Fall which may result in injury
Bleeding within the skull
Circulatory problems
Loss of vision
Loss of sex drive (libido)
Passing large amounts of urine with bone pain and weakness, which may be symptoms of a kidney disorder (Fanconi syndrome)
Yellow pigmentation to the skin, mucus membrane or eyes (jaundice), pale coloured stools, dark coloured urine, skin itch, rash, pain or swelling of the stomach – these may be symptoms of injury to the liver (hepatic failure)
Stomach pain, bloating, or diarrhoea, which may be symptoms of inflammation in the large intestine (called colitis or caecitis)
Damage to the cells of the kidney (called renal tubular necrosis)
Changes to the colour of your skin, sensitivity to sunlight
Tumour lysis syndrome - metabolic complications that can occur during treatment of cancer and sometimes even without treatment. These complications are caused by the break-down products of dying cancer cells and may include the following: changes to blood chemistry; high potassium, phosphorus, uric acid, and low calcium consequently leading to changes in kidney function, heart beat, seizures, and sometimes death.
Increase in blood pressure within blood vessels that supply the lungs (pulmonary hypertension).
Sudden, or mild but worsening pain in the upper stomach and/or back, which remains for a few days, possibly accompanied by nausea, vomiting, fever and a rapid pulse – these symptoms may be due to inflammation of the pancreas.
Wheezing, shortness of breath or a dry cough, which may be symptoms caused by inflammation of the tissue in the lungs.
Rare cases of muscle breakdown (muscle pain, weakness or swelling) which can lead to kidney problems (rhabdomyolysis) have been observed, some of them when Revlimid is administered with a statin (a type of cholesterol lowering medicines).
A condition affecting the skin caused by inflammation of small blood vessels, along with pain in the joints and fever (leukocytoclastic vasculitis).
Breakdown of the wall of the stomach or gut. This may lead to very serious infection. Tell your doctor if you have severe stomach pain, fever, nausea, vomiting, blood in your stool, or changes in bowel habits.
Viral infections, including herpes zoster (also known as ‘shingles’, a viral disease that causes a painful skin rash with blisters) and recurrence of hepatitis B infection (which can cause yellowing of the skin and eyes, dark brown-colored urine, right-sided stomach pain, fever and feeling nauseous or being sick).
Rejection of solid organ transplant (such as kidney, heart).
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system listed in AppendixV. By reporting side effects you can help provide more information on the safety of this medicine.
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date, which is stated on the blister and on the carton after ‘EXP’. The expiry date refers to the last day of that month.
This product does not require any special storage conditions.
Do not use this medicine if you notice any damage or signs of tampering to the pack.
Do not throw away any medicines via wastewater or household waste. Please return unused medicines to your pharmacist. These measures will help protect the environment.
Revlimid 2.5 mg hard capsules:
The active substance is lenalidomide. Each capsule contains 2.5 mg of lenalidomide.
The other ingredients are:
capsule contents: anhydrous lactose (see section 2), microcrystalline cellulose, croscarmellose sodium and magnesium stearate
capsule shell: gelatine, titanium dioxide (E171), indigo carmine (E132) and yellow iron oxide (E172)
printing ink: shellac, propylene glycol (E1520), potassium hydroxide and black iron oxide (E172).
Revlimid 5 mg hard capsules:
The active substance is lenalidomide. Each capsule contains 5 mg of lenalidomide.
The other ingredients are:
capsule contents: anhydrous lactose (see section 2), microcrystalline cellulose, croscarmellose sodium and magnesium stearate
capsule shell: gelatine and titanium dioxide (E171)
printing ink: shellac, propylene glycol (E1520), potassium hydroxide and black iron oxide (E172).
Revlimid 7.5 mg hard capsules:
The active substance is lenalidomide. Each capsule contains 7.5 mg of lenalidomide.
The other ingredients are:
capsule contents: anhydrous lactose (see section 2), microcrystalline cellulose, croscarmellose sodium and magnesium stearate
capsule shell: gelatine, titanium dioxide (E171) and yellow iron oxide (E172)
printing ink: shellac, propylene glycol (E1520), potassium hydroxide and black iron oxide (E172).
Revlimid 10 mg hard capsules:
The active substance is lenalidomide. Each capsule contains 10 mg of lenalidomide.
The other ingredients are:
capsule contents: anhydrous lactose (see section 2), microcrystalline cellulose, croscarmellose sodium and magnesium stearate
capsule shell: gelatine, titanium dioxide (E171), indigo carmine (E132) and yellow iron oxide (E172)
printing ink: shellac, propylene glycol (E1520), potassium hydroxide and black iron oxide (E172).
Revlimid 15 mg hard capsules:
The active substance is lenalidomide. Each capsule contains 15 mg of lenalidomide.
The other ingredients are:
capsule contents: anhydrous lactose (see section 2), microcrystalline cellulose, croscarmellose sodium and magnesium stearate
capsule shell: gelatine, titanium dioxide (E171) and indigo carmine (E132)
printing ink: shellac, propylene glycol (E1520), potassium hydroxide and black iron oxide (E172).
Revlimid 20 mg hard capsules:
The active substance is lenalidomide. Each capsule contains 20 mg of lenalidomide.
The other ingredients are:
capsule contents: anhydrous lactose (see section 2), microcrystalline cellulose, croscarmellose sodium and magnesium stearate
capsule shell: gelatine and titanium dioxide (E171), indigo carmine (E132) and yellow iron oxide (E172)
printing ink: shellac, propylene glycol (E1520), potassium hydroxide and black iron oxide (E172).
Revlimid 25 mg hard capsules:
The active substance is lenalidomide. Each capsule contains 25 mg of lenalidomide.
The other ingredients are:
capsule contents: anhydrous lactose (see section 2), microcrystalline cellulose, croscarmellose sodium and magnesium stearate
capsule shell: gelatine and titanium dioxide (E171)
printing ink: shellac, propylene glycol (E1520), potassium hydroxide and black iron oxide (E172).
Revlimid 2.5 mg hard capsules are blue-green/white, with ‘REV 2.5 mg’ written on them.
The capsules are provided in packs. Each pack contains one or three blisters, each blister with seven capsules. This gives a total of 7 or 21 capsules per pack.
Revlimid 5 mg hard capsules are white, with ‘REV 5 mg’ written on them.
The capsules are provided in packs. Each pack contains one or three blisters, each blister with seven capsules. This gives a total of 7 or 21 capsules per pack.
Revlimid 7.5 mg hard capsules are pale yellow/white, with ‘REV 7.5 mg’ written on them.
The capsules are provided in packs. Each pack contains one or three blisters, each blister with seven capsules. This gives a total of 7 or 21 capsules per pack.
Revlimid 10 mg hard capsules are blue-green/pale yellow, with ‘REV 10 mg’ written on them.
The capsules are provided in packs. Each pack contains one or three blisters, each blister with seven capsules. This gives a total of 7 or 21 capsules per pack.
Revlimid 15 mg hard capsules are pale blue/white, with ‘REV 15 mg’ written on them.
The capsules are provided in packs. Each pack contains one or three blisters, each blister with seven capsules. This gives a total of 7 or 21 capsules per pack.
Revlimid 20 mg hard capsules are blue-green/pale blue, with ‘REV 20 mg’ written on them.
The capsules are provided in packs. Each pack contains one or three blisters, each blister with seven capsules. This gives a total of 7 or 21 capsules per pack.
Revlimid 25 mg hard capsules are white, with ‘REV 25 mg’ written on them.
The capsules are provided in packs. Each pack contains one or three blisters, each blister with seven capsules. This gives a total of 7 or 21 capsules per pack.
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There are also links to other websites about rare diseases and treatments.