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AstraZeneca

Optison
perflutren

Package leaflet: Information for the user


OPTISON 0.19 mg/ml dispersion for injection

Perflutren-containing microspheres


Read all of this leaflet carefully before you start using this medicine because it contains important information for you.


Immediately after injection of OPTISON, 10 ml of sodium chloride 9 mg/ml (0.9%) solution for injection or glucose 50 mg/ml (5%) solution for injection should be injected at a rate of 1 ml/s.


Alternatively, the flushing may be performed by infusion. The infusion set should then be attached to the three-way stopcock and intravenous infusion started at a ”to keep open” (TKO) rate. Immediately after OPTISON injection the intravenous infusion should be wide open until contrast begins to fade from the left ventricle. The infusion should then be returned to a TKO rate.